Seroseps’ dry gas ClO2 decontamination technology is driving a paradigm shift in the way we approach and implement sterilisation and chemical decontamination across industries.
An EPA registered steriliser, dry gas chlorine dioxide eliminates all forms of microbial life, providing >106 log reduction of all organisms including bacterial spores, small round viruses, catalase expressing organisms, such as Mycobacteria and parasites such as pinworm1.
Complete distribution and Penetration
Being a true gas at standard temperature and pressure and having a particle size of 125 picometres, all surfaces within an area will be exposed to the correct amount of ClO2 for sterilisation regardless of area contents, size or temperature gradient. Following Henrys law, ClO2 does not disassociate in liquids and will sterilise spillages with equal efficacy.
Safe & environmentally friendly
ClO2 Dry gas is non-carcinogenic, non-explosive, leaves no residues and has an odour at a safe concentration. Once aerated, ClO2 breaks down in UV to environmentally friendly by-products. Unlike Ethylene oxide, it is not a derivative of petrochemicals nor is it a chlorinating agent like elemental chlorine. Toxic pollutants such as trihalomethanes (THM`s) are not emitted during this process.
Rapid and Flexible
Our ClO2 has the fastest cycle time of any fumigant, fumigating whole facilities in <3 hours. With a rapid aeration and no clean up, dry gas ClO2 allows for instant re-use of target areas. Up to 15 areas can be decontaminated at one time, providing an improvement in throughput as well as speed.
Fully monitored process
The ClO2 concentration is monitored in real-time using spectrophotometer for each cycle. This immediate parametric validation that the required exposure time was achieved and the cycle was a success, this also confirms areas as safe to re-enter. Providing an option to move away from routine use of Biological Indicators.
Chlorine Dioxide is not corrosive, however, previous ClO2 technologies include a “wet” generation method that yields corrosive residual acidic by-product`s. ClO2 itself is not corrosive. Unlike these previous technologies, our ClO2 is produced as a dry gas meaning no acidic residues are exposed to the target environment.
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Benefits for Pharma
Dry ClO2 gas provides an augmented solution for contamination control within the Pharmaceutical settings. <15 isolators and/or rooms can be sterilised at once with Isolator cycles <15 minutes and clean rooms completed within 2 hours. In addition to improving efficiency, ClO2 is also suited to robotics and sensitive equipment, being able to sterilize surfaces without putting the machinery at risk2.
Moulds and Biofilms
The persistence of moulds can cause significant inefficiencies within pharmaceutical practice. Chlorine dioxide is proven effective in inactivating biofilms and eliminating moulds, adding this step to standard cleaning practice will augment the control of this type of contamination.
Sterilisation of isolators and clean rooms
Dry ClO2 gas cycles sterilise isolators in <15 minutes and rooms <2 hours with immediate cycle validation and proof of re-use/re-entry. Unlike other methods, the system can be integrated into facilities or adapted to sterilise multiple isolators/rooms at once within the same time frame, enhancing on the throughput associated with sterilisation in addition to reducing turn around times.
benefits FOR medical
Serosep are utilizing the power of our chlorine dioxide dry gas technology for the sterilisation of medical devices following it`s FDA approval as an alternative to EO.
Endoscopes: Being a true gas at STP, ClO2 provides ultimate penetration of endoscopes, ensuring all surfaces will be exposed to the required concentration of ClO2 to ensure sterility. Cycle time(s) can be <15 minutes, with the ability for multiple endoscopes to be sterilised at once.
Chlorine Dioxide dry gas has the ability to enable a paradigm shift from HLD to sterility and this is endeavor is a focus of Serosep moving forward.
Contract sterilisation services
Being a true gas at STP, ClO2 provides a direct alternative to ethylene oxide which is safer and faster, circumventing the cancerous and explosive nature of EO whilst also reducing TAT`s to hours instead of days. Unlike EO, ClO2 is compatible with a range of sensitive devices including those with batteries, therefore It also widens the reach low-temperature sterilisation with regards to product range.
Timertag is a patented alert system providing a compliance aid within the medical sector ensuring healthcare workers are alerted to expiries of medical devices such as IV catheters, endoscopes etc. Clinical trials have shown Timertag improved peripheral compliance from 30% to >80% to reduce bloodstream infections associated with indwelling medical devices. Timertag is a simple, cost effective option to improve compliance within healthcare, timers can be in both disposable and re-usable format4.
benefits for healthcare
Serosep are utilizing the power of our chlorine dioxide dry gas technology to provide a paradigm shift in the way sterilisation and chemical decontamination processes are achieved5.
Following Formaldehyde’s classification as a class 1B carcinogen. ClO2 dry gas provides a true gas alternative for sterilisation of containment laboratories and associated equipment which is not only non-carcinogenic but is also quicker with improved quality control.
ClO2 dry gas provides a flexible, scalable and rapid option for hospital pharmacy contamination control. One unit can serve up to 15 locations, allowing isolators and clean rooms to be sterilized at one time, individually or in bespoke combinations. Being well suited to sensitive equipment, this solution offers hospital pharmacies a method which is able to adapt to their dynamic environments without constant re-validation or need to purchase multiple units.
wards and side rooms
Providing the required infrastructure is present, ClO2 dry gas provides a rapid solution to sterilise wards and side rooms following identification of a hospital acquired infection. This allows for quick reaction to nosocomial outbreaks, including those caused by difficult organisms such as Clostridium difficile or Catalase expressing Staphylococci.
Benefits for Life Sciences
Dry gas ClO2 provides the perfect option for research institutes including those with animal laboratories as ClO2 is effective in eliminating parasites such as pinworms and their eggs. Being a true gas, all microbial life including pinworms can be eliminated from a facility without the requirement to remove contents and equipment from the target space. This solution aims to improve on the efficiencies and practicalities that are sometimes fragile when implementing decontamination in these facilities.
Infectious diseases and parasitic agents such as Pinworm infestations are common in Veterinary Centres and Animal Research Facilities. Infections and Infestation can be significantly detrimental to facility research, financial losses, facility reputation and to the health of the animal population in general. A well-coordinated, effective and consistent gaseous decontamination method is required for control of contamination of these facilities. With the onset of Germ-free facilities, the requirement for a true gas is now paramount to avoid inconsistency of penetrations by vapors, as such C lO2 provides the augmented alternatives to Peracetic acid whilst also avoiding the cancerous properties of formaldehyde6.
Infestations of Syphaccia spp and their ova within animal facilities can cripple processing. Although treatment with Ivermectin and Fenbendazole can rid the animal itself of pinworm, the eggs can survive for weeks outside the host, penetrate into equipment and even HVAC systems, thorough deep cleaning methods are essential to mitigate contamination. Heat Sterilisation and Ethylene oxide gas are two of three validated methods for pinworm egg inactivation, however, neither can be applied to an open environment. The third method is dry gas chlorine dioxide which is proven to eliminate both pinworms and their eggs from all corners and equipment within an environment (Czarra et al., 2014)7. Combining engineering controls, treatment schedules and ClO2 decontamination, Serosep are able to structure pinworm eradication from the facility in question.
Dry Gas ClO2 is a recognized sterilisation method for biosafety cabinets and containment facilities. Being non-cancerous, quicker and with enhanced regulatory features, ClO2 is a dry gas is a direct alternative for formaldehyde following its classification as a carcinogen. Being a true gas, ClO2 penetrates the HEPA filter consistently therefore the cycle remains the same for all rooms/cabinets within the facility. Being non-corrosive, the system is also suitable for use on complex and expensive machinery frequently used within research facilities, such as Electron-microscopes and Mass Spectrometry units8.